Next generation microbiome analysis

Health begins where you can’t see it.

A precision microbiome test that turns trillions of gut microbes into a clear, science-backed plan for energy, mood, immunity and metabolism.

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★★★★★ 4.8 from 8,000+ members

What we measure

One test. The whole gut story.

Most microbiome tests stop at “diversity.” Brilliant Biome cross-references your full microbial signature against 80,000+ published studies to surface what’s actually driving how you feel.

01

Gut–brain axis

Mood, focus, sleep, brain fog — mapped to the microbes that influence them.

SerotoninGABAVagal tone
02

Energy & metabolism

Short-chain fatty acids, glucose response patterns, mitochondrial co-factors.

SCFAsBile acidsB vitamins
03

Immunity & inflammation

Microbial drivers of systemic inflammation, allergy response, and barrier health.

LPSAkkermansiaIgA
04

Digestion & comfort

What’s behind bloating, irregularity, food sensitivities — and what to eat instead.

BloatingFODMAPLactose
05

Hormones & longevity

Estrogen recycling, thyroid co-factors, biological age signals.

EstrobolomeTMAAging
06

Disease risk signals

Early microbial associations with IBS, IBD, metabolic syndrome, anxiety.

IBSIBDAnxiety

How it works

Get clarity on your gut in four weeks.

No clinic visits. No 80-page report. Just a precise read on what’s happening inside you and exactly what to do about it.

01

Order your kit

Ships in 2 days. Sample collection takes about 5 minutes at home.

02

We sequence

Whole-genome shotgun sequencing in our CLIA-certified lab partner.

03

AI cross-references

Our model maps your microbes against the latest peer-reviewed research.

04

You get a plan

A clear protocol — foods, supplements, lifestyle — plus a 30-min consult.

The science

Built on peer-reviewed studies. Billions of datapoints. Updated weekly.

The microbiome research field publishes faster than any clinician can keep up. Our AI reads it for you — and only surfaces recommendations with established evidence behind them.

  • Whole-genome shotgun sequencingMore resolution than 16S rRNA — strain-level identification.
  • Evidence-tiered recommendationsEvery suggestion is tagged based on the evidence - Established / Emerging / Limited research.
  • Reviewed by scientific and clinical expertsWe know what matters.

Read the science page →

Sample citations

01

Akkermansia muciniphila and metabolic health in humans

Nature Medicine · 2024 · n=2,118

02

Microbiome-derived butyrate in colonic homeostasis

Cell Host & Microbe · 2024

03

Gut-brain serotonin precursors and mood disorders

Gastroenterology · 2023 · n=4,402

04

Short-chain fatty acids and insulin sensitivity

Diabetes Care · 2024

For practitioners

Microbiome data your patients will actually act on.

Brilliant Biome for Practitioners gives functional, integrative, and longevity clinicians a clinical-grade dashboard, white-labeled patient reports, and direct lab access — without the operational lift.

  • Order, track, and reviewpatient kits from one workspace.
  • Co-branded reportswith your protocols and recommendations.
  • Bulk pricingand HIPAA-compliant data exports.
Apply to the partner program →
Patient roster 12 active
JMJ. Martinez · GI rebalance
On track
RTR. Tate · Metabolic optimize
New report
EWE. Wong · Hormone protocol
On track
DKD. Kim · Anxiety + sleep
Needs review
LPL. Park · Postnatal recovery
On track

Members

What people noticed first.

“After two years of vague gut issues and ‘normal’ bloodwork, this was the first thing that actually pointed at a cause. Three weeks in I’d dropped the bloating and slept through the night.”

SM
Sarah M.
Member · 8 months

“I run a functional medicine practice. The reports are clinical-grade and patients actually read them. That alone is worth the partnership.”

DR
Dr. R. Patel, MD
Functional medicine, Austin

“The recommendations are specific. Not ‘eat more fiber’ — actual foods, actual amounts, with the studies behind them. I appreciated being treated like an adult.”

JL
Jordan L.
Member · 1 year

FAQ

Questions, answered.

  • We use whole-genome shotgun sequencing instead of 16S — that's strain-level resolution, not just family- or genus-level.

    Our AI cross-references your results against the live scientific literature, and every recommendation is tagged by evidence strength.

    You also get a 30-minute consult with a microbiome coach

  • Yes — and many of them already use us. Reports are designed to be readable by clinicians, with clear methodology, citations, and a separate practitioner-facing summary you can hand off.

  • We’re working on this! It should be available, soon!

  • We recommend retesting every 4–6 months while you're actively shifting your protocol, then annually for maintenance.

  • A pre-paid sample collection kit, return shipping, lab analysis, your full report, a personalized protocol, and a 30-minute consult with a registered clinician.

Start where it counts

You don’t have to guess what your gut is doing.

Order your kit today. Free shipping. Results in about three weeks.

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